Significance The Biological Activity to Pyrimidine Analogues

Abstract

Heterocyclic organic compound make up an extremely important class of compounds." In fact, more than half of all known organic compounds are belong for this class. Many inbred drugs such as morphine, atropine, Vitamin B1 and folic acid are heterocycles compounds and used for treatment of various diseases. Some other synthetic drugs such as barbiturates , capreomycine , flucytosine , pyrantal pamoate, azidothymidine, antipyrine , and the HIV drug are also clasified as very potent heterocycles". pyrimidine is one of the most important Heterocycles compounds, most potent pyrimidines used to treat of various diseases such as cancer, Leukemia . pyrimidine also represents the backbone of RNA and DNA.