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Objectives: This clinical study to evaluate the role of antibiotic prophylaxis in prevention of wound infection in laparoscopic cholecystectomy. And to identify the risk factors for infection. Methods: Prospective study was done from 1st June to 31st December 2017 in Al-Rabee private hospital for 110 patients under went laparoscopic cholecystectomy (LC ). Group A: the received cefatriaxon 1gm at the time of anesthesia. Group B: not receive the cefatriaxon. Results: Wound infections were discovered in 3 (2.72%) patients of all cases, 1 (1.66%) from group A and (4%) from group B 30-50 year most common age incidence, gallstone more common in the females. Conclusion: Prophylactic antibiotic are not so necessary to prevent wound infection in patients undergoing laparoscopic cholecystectomy.
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