Effect of Bisphenol A on Some of Antioxidants in White Male Rats

Abstract

Objectives: The study aimed to determine the effect of bisphenol A on some antioxidants in white male rats. Methods: In this experiment, 24 rats were divided into three groups of 8 replicates per group for 8 weeks. Two groups were treated orally with two different concentrations of bisphenol A, 15 and 30 mg / kg body weight. The control group was treated with corn oil. The effect of bisphenol A on serum GSH, MDA, CAT and SOD, was studied. Results: The results showed an increase in MDA level and a decrease in GSH, CAT and SOD levels in groups treated with bisphenol concentrations compared with control group. Conclusion: These results suggest that BPA exposure might induce oxidative stress and its complications in adult male rats.